It can also predict secondary structures common to two, unaligned sequences, which is much more accurate than single sequence secondary structure prediction. It also can be used to predict bimolecular structures and can predict the equilibrium binding affinity of an oligonucleotide to a structured RNA target. It includes algorithms for secondary structure prediction, including facility to predict base pairing probabilities. RNAstructure is a complete package for RNA and DNA secondary structure prediction and analysis. RNAstructure, Version 6.3: Updated Ap( change log)